495-60-3

495-60-3 structure

Name: zingiberene
Chemical Name: zingiberene
CAS Number: 495-60-3
Molecular Formula: C₁₅H₂₄
Molecular Weight: 204.35100
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2018-06-21 21:10:08
Modify Date: 2024-01-08 18:27:27
Zingiberene (α-Zingiberene) is a monocyclic sesquiterpene which is the predominant constituent of ginger with oil content (Zingiber officinale). Neuroprotective potential[1]. Zingiberene triggers autophagy. Anticancer activity[2].

Name	zingiberene
Synonyms	Zingiberene (5R)-2-methyl-5-[(2S)-6-methylhept-5-en-2-yl]cyclohexa-1,3-diene EINECS 207-804-2 Alpha-Zingiberene Zingiberene from ginger

Description	Zingiberene (α-Zingiberene) is a monocyclic sesquiterpene which is the predominant constituent of ginger with oil content (Zingiber officinale). Neuroprotective potential[1]. Zingiberene triggers autophagy. Anticancer activity[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
In Vitro	Zingiberene (6.25, 12.5, 25, 50 and 100 μg/mL; 24 hours) attenuates hydrogen peroxide-induced toxicity in neuronal cells[1]. Zingiberene (0, 10, 20 and 40 µM; 24 hours) considerably inhibits the proliferation of Colon cancer (CC) cells[2].
References	[1]. B Togar, et al. Zingiberene attenuates hydrogen peroxide-induced toxicity in neuronal cells. Hum Exp Toxicol. 2015 Feb;34(2):135-44. [2]. Hai Chen, Zingiberene inhibits in vitro and in vivo human colon cancer cell growth via autophagy induction, suppression of PI3K/AKT/mTOR Pathway and caspase 2 deactivation. J BUON. Jul-Aug 2019;24(4):1470-1475.