Name | 2-[(5-Ethyl-4-hydroxy-6-methyl-2-pyrimidinyl)sulfanyl]-N-[4-(4-me thoxyphenyl)-1,3-thiazol-2-yl]acetamide |
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Synonyms | T16Ainh-A01 |
Description | T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2]. |
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Related Catalog | |
Target |
TMEM16A[1]. |
References |
Molecular Formula | C19H20N4O3S2 |
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Molecular Weight | 416.52 |
Exact Mass | 416.09800 |
PSA | 154.26000 |
LogP | 4.56540 |
RIDADR | NONH for all modes of transport |
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