Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (R)-Colchicine
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+)-Colchicine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

75520-89-7

75520-89-7 structure

75520-89-7 structure

Name: (+)-Colchicin
Chemical Name: N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
CAS Number: 75520-89-7
Molecular Formula: C₂₂H₂₅NO₆
Molecular Weight: 399.43700
Create Date: 2016-02-24 06:19:34
Modify Date: 2025-08-20 20:55:32

Name	N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Synonyms	(+)-Colchicin COLCHICINE,(+) Acetamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(R) (R)-7-Acetylamino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-on Lopac-C-9754 Colchicine,(R)-Isomer

Density	1.25g/cm3
Boiling Point	726ºC at 760 mmHg
Melting Point	106-132ºC
Molecular Formula	C₂₂H₂₅NO₆
Molecular Weight	399.43700
Flash Point	392.9ºC
Exact Mass	399.16800
PSA	83.09000
LogP	3.26250
Index of Refraction	1.584

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0705000

CHEMICAL NAME :: Colchicine, (+)-

CAS REGISTRY NUMBER :: 75520-89-7

LAST UPDATED :: 199409

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H25-N-O6

MOLECULAR WEIGHT :: 399.48

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 49 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981

73307-44-5 structure

73307-44-5

~%

75520-89-7 structure

75520-89-7

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

209810-38-8 structure

209810-38-8

~%

75520-89-7 structure

75520-89-7

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

102491-73-6 structure

102491-73-6

~%

75520-89-7 structure

75520-89-7

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

102491-70-3 structure

102491-70-3

~%

75520-89-7 structure

75520-89-7

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

102491-71-4 structure

102491-71-4

~%

75520-89-7 structure

75520-89-7

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

3482-37-9 structure

3482-37-9

~%

75520-89-7 structure

75520-89-7

Literature: Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261

186581-53-3 structure

186581-53-3

477-27-0 structure

477-27-0

~%

75520-89-7 structure

75520-89-7

Literature: Roesner et al. Journal of Medicinal Chemistry, 1981 , vol. 24, p. 257,260

186581-53-3 structure

186581-53-3

477-27-0 structure

477-27-0

~%

75520-89-7 structure

75520-89-7

102419-93-2 structure

102419-93-2

Literature: Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261

7469-68-3 structure

7469-68-3

~%

75520-89-7 structure

75520-89-7

Literature: Corrodi; Hardegger Helvetica Chimica Acta, 1957 , vol. 40, p. 193,198, 199

Precursor 9
73307-44-5 209810-38-8 102491-73-6 102491-70-3
102491-71-4 3482-37-9 186581-53-3 477-27-0
7469-68-3
DownStream 0

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