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75520-89-7

75520-89-7 structure
75520-89-7 structure
  • Name: (+)-Colchicin
  • Chemical Name: N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
  • CAS Number: 75520-89-7
  • Molecular Formula: C22H25NO6
  • Molecular Weight: 399.43700
  • Create Date: 2016-02-24 06:19:34
  • Modify Date: 2024-01-05 18:35:00
Name N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Synonyms (+)-Colchicin
COLCHICINE,(+)
Acetamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(R)
(R)-7-Acetylamino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-on
Lopac-C-9754
Colchicine,(R)-Isomer
Density 1.25g/cm3
Boiling Point 726ºC at 760 mmHg
Melting Point 106-132ºC
Molecular Formula C22H25NO6
Molecular Weight 399.43700
Flash Point 392.9ºC
Exact Mass 399.16800
PSA 83.09000
LogP 3.26250
Index of Refraction 1.584

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH0705000
CHEMICAL NAME :
Colchicine, (+)-
CAS REGISTRY NUMBER :
75520-89-7
LAST UPDATED :
199409
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H25-N-O6
MOLECULAR WEIGHT :
399.48
WISWESSER LINE NOTATION :
L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49 mg/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981
73307-44-5 structure

73307-44-5

~%

75520-89-7 structure

75520-89-7
Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521
209810-38-8 structure

209810-38-8

~%

75520-89-7 structure

75520-89-7
Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521
102491-73-6 structure

102491-73-6

~%

75520-89-7 structure

75520-89-7
Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521
102491-70-3 structure

102491-70-3

~%

75520-89-7 structure

75520-89-7
Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521
102491-71-4 structure

102491-71-4

~%

75520-89-7 structure

75520-89-7
Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521
3482-37-9 structure

3482-37-9

~%

75520-89-7 structure

75520-89-7
Literature: Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261
186581-53-3 structure

186581-53-3
477-27-0 structure

477-27-0

~%

75520-89-7 structure

75520-89-7
Literature: Roesner et al. Journal of Medicinal Chemistry, 1981 , vol. 24, p. 257,260
186581-53-3 structure

186581-53-3
477-27-0 structure

477-27-0

~%

75520-89-7 structure

75520-89-7

102419-93-2 structure

102419-93-2
Literature: Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261
7469-68-3 structure

7469-68-3

~%

75520-89-7 structure

75520-89-7
Literature: Corrodi; Hardegger Helvetica Chimica Acta, 1957 , vol. 40, p. 193,198, 199

Chemsrc provides CAS#:75520-89-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 75520-89-7 | Chemsrc address: https://www.chemsrc.com/en/baike/1041883.html

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