72214-67-6
72214-67-6 structure
- Name: RRD-251 hydrochloride
- Chemical Name: (2,4-dichlorophenyl)methyl carbamimidothioate,hydrochloride
- CAS Number: 72214-67-6
- Molecular Formula: C8H9Cl3N2S
- Molecular Weight: 271.59400
- Create Date: 2016-04-22 02:44:06
- Modify Date: 2024-04-03 11:57:34
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RRD-251 hydrochloride is a small molecule disruptor of Rb/Raf-1 interaction, potently and selectively disrupts the Rb/Raf-1 (IC50=77 nM) but not Rb/E2F, Rb/prohibitin, Rb/cyclin E, and Rb/HDAC binding.
| Name | (2,4-dichlorophenyl)methyl carbamimidothioate,hydrochloride |
|---|---|
| Synonyms | RRD-251 hydrochloride |
| Density | 1.47g/cm3 |
|---|---|
| Boiling Point | 345.3ºC at 760 mmHg |
| Molecular Formula | C8H9Cl3N2S |
| Molecular Weight | 271.59400 |
| Flash Point | 162.6ºC |
| Exact Mass | 269.95500 |
| PSA | 75.17000 |
| LogP | 4.72210 |
| Index of Refraction | 1.643 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261 |
| RIDADR | NONH for all modes of transport |
|
~98%
72214-67-6 |
| Literature: UNIVERSITY OF SOUTH FLORIDA Patent: WO2007/62222 A2, 2007 ; Location in patent: Page/Page column 47; 49; 70 ; |
| Precursor 1 | |
|---|---|
| DownStream 1 | |
