Shanghai Nianxing Industrial Co., Ltd
China
Product Name: α-hydroxy Metoprolol
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: α-hydroxy Metoprolol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

56392-16-6

56392-16-6 structure

56392-16-6 structure

Name: UNII:C19D0413EL
Chemical Name: α-Hydroxy Metoprolol
CAS Number: 56392-16-6
Molecular Formula: C₁₅H₂₅NO₄
Molecular Weight: 283.363
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2018-08-26 18:01:14
Modify Date: 2025-08-25 18:28:15
a-Hydroxymetoprolol is a metabolite of metoprolol. The adrenoreceptor blocking effect of a-Hydroxymetoprolol on metoprolol is almost zero[1].

Name	α-Hydroxy Metoprolol
Synonyms	1-[4-(1-Hydroxy-2-methoxyethyl)phenoxy]-3-(isopropylamino)-2-propanol 3-[4-(1-Hydroxy-2-methoxyethyl)phenoxy]-1-isopropylamino-2-propanol Benzenemethanol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-α-(methoxymethyl)- α-HYDROXYMETOPROLOL 1-[4-(1-hydroxy-2-methoxyethyl)phenoxy]-3-(isopropylamino)propan-2-ol UNII:C19D0413EL

Description	a-Hydroxymetoprolol is a metabolite of metoprolol. The adrenoreceptor blocking effect of a-Hydroxymetoprolol on metoprolol is almost zero[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Hoffmann KJ, et al. The effect of impaired renal function on the plasma concentration and urinary excretion of metoprolol metabolites. Clin Pharmacokinet. 1980 Mar-Apr;5(2):181-91.

Density	1.1±0.1 g/cm3
Boiling Point	437.6±45.0 °C at 760 mmHg
Melting Point	65-67ºC
Molecular Formula	C₁₅H₂₅NO₄
Molecular Weight	283.363
Flash Point	218.4±28.7 °C
Exact Mass	283.178345
PSA	70.95000
LogP	0.72
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.524
Storage condition	-20°C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA4907000

CHEMICAL NAME :: Benzenemethanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-alpha-( methoxymethyl)-

CAS REGISTRY NUMBER :: 56392-16-6

LAST UPDATED :: 198809

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H25-N-O4

MOLECULAR WEIGHT :: 283.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979

RIDADR	NONH for all modes of transport

110458-45-2 structure

110458-45-2

~95%

56392-16-6 structure

56392-16-6

Literature: Shetty, H. Umesha; Nelson, Wendel L. Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 55 - 59

2491-38-5 structure

2491-38-5

~%

56392-16-6 structure

56392-16-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 1 p. 55 - 59

32136-81-5 structure

32136-81-5

~%

56392-16-6 structure

56392-16-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 1 p. 55 - 59

110458-44-1 structure

110458-44-1

~%

56392-16-6 structure

56392-16-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 1 p. 55 - 59

110458-43-0 structure

110458-43-0

~%

56392-16-6 structure

56392-16-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 1 p. 55 - 59

110458-42-9 structure

110458-42-9

~%

56392-16-6 structure

56392-16-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 1 p. 55 - 59

51384-51-1 structure

51384-51-1

~%

56392-16-6 structure

56392-16-6

Literature: European Journal of Clinical Pharmacology, , vol. 59, # 5-6 p. 429 - 442

Precursor 6
110458-45-2 2491-38-5 32136-81-5 110458-44-1
110458-43-0 51384-51-1
DownStream 0

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