Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT
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Purity: 98.0%
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118253-05-7

118253-05-7 structure

Name: Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt
Chemical Name: [(3S)-7-amino-2-oxo-3-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]heptyl] 2,4,6-trimethylbenzoate,2,2,2-trifluoroacetic acid
CAS Number: 118253-05-7
Molecular Formula: C₃₄H₄₁N₃O₆
Molecular Weight: 587.71
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-07-25 15:58:33
Modify Date: 2024-01-09 09:48:45
Z-FK-ck (Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone) is a potent and selective gingipain-K-specific inhibitor. Z-FK-ck prolongs plasma thrombin time (TT) in a dose- and time-dependent manner[1].

Name	[(3S)-7-amino-2-oxo-3-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]heptyl] 2,4,6-trimethylbenzoate,2,2,2-trifluoroacetic acid
Synonyms	(S)-7-Amino-3-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)-2-oxoheptyl 2,4,6-trimethylbenzoate 2,2,2-trifluoroacetate

Description	Z-FK-ck (Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone) is a potent and selective gingipain-K-specific inhibitor. Z-FK-ck prolongs plasma thrombin time (TT) in a dose- and time-dependent manner[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Imamura T, et, al. Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites. Infect Immun. 1995 Dec;63(12):4877-82.