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116-17-6

116-17-6 structure
116-17-6 structure

Name Triisopropyl phosphite
Synonyms EINECS 204-130-0
tripropan-2-yl phosphite
Medronic acid impurity A
Triisopropyl phosphite
Phosphorous acid, triisopropyl ester (8CI)
Phosphorous acid, tris(1-methylethyl) ester
MFCD00008874
Density 0.914
Boiling Point 181.4±0.0 °C at 760 mmHg
Molecular Formula C9H21O3P
Molecular Weight 208.235
Flash Point 67.8±0.0 °C
Exact Mass 208.122833
PSA 41.28000
LogP 1.71
Vapour Pressure 1.2±0.3 mmHg at 25°C
Index of Refraction n20/D 1.411(lit.)
Water Solubility Insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TH2800000
CHEMICAL NAME :
Phosphorous acid, tris(1-methylethyl) ester
CAS REGISTRY NUMBER :
116-17-6
BEILSTEIN REFERENCE NO. :
1701528
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H21-O3-P
MOLECULAR WEIGHT :
208.27
WISWESSER LINE NOTATION :
1Y1&OPOY1&1&OY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
167 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
50 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315
Precautionary Statements Missing Phrase - N15.00950417
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;
Risk Phrases R25;R38;R68
Safety Phrases S37-S46-S45-S36/37
RIDADR UN 3278 6.1/PG 3
WGK Germany 3
RTECS TH2800000
Packaging Group III
Hazard Class 3

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116-17-6 structure

116-17-6

Literature: Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 237,241 Chem. Zentralbl., , vol. 121, p. 8713 Annali di Chimica (Rome, Italy), , vol. 43, p. 568,571,572 Industrial and Engineering Chemistry, , vol. 43, p. 876,878

~0%

116-17-6 structure

116-17-6

Literature: Collins, David J.; Drygala, Peter F.; Swan, John M. Australian Journal of Chemistry, 1983 , vol. 36, # 12 p. 2517 - 2536

~65%

116-17-6 structure

116-17-6

Literature: Al'fonsov, V. A.; Pudovik, D. A.; Musin, R. Z.; Nazmutdinova, V. N.; Efremov, Yu. Ya.; et al. J. Gen. Chem. USSR (Engl. Transl.), 1988 , vol. 58, # 8 p. 1734 - 1740,1548 - 1553

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116-17-6 structure

116-17-6

Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 11 p. 2159 - 2165

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116-17-6 structure

116-17-6

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 8 p. 1734 - 1740,1548 - 1553

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Detail
Literature: Journal of the Chemical Society, , p. 422,424

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116-17-6 structure

116-17-6

Literature: Journal of the Chemical Society, , p. 1466

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Detail
Literature: Zhurnal Obshchei Khimii, , vol. 17, p. 2129,2132 Chem.Abstr., , p. 4546