41906-86-9
41906-86-9 structure
- Name: nitrocefin
- Chemical Name: nitrocefin
- CAS Number: 41906-86-9
- Molecular Formula: C21H16N4O8S2
- Molecular Weight: 516.504
- Create Date: 2018-09-20 16:48:45
- Modify Date: 2025-08-24 18:52:25
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Nitrocefin is a chromogenic β-lactamase substrate that undergoes distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics[1].
| Name | nitrocefin |
|---|---|
| Synonyms |
(6R-(3(E),6a,7b))-3-(2-(2,4-Dinitrophenyl)ethenyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, (6R,7R)- nitrocefin (6R,7R)-3-[(E)-2-(2,4-Dinitrophenyl)vinyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Description | Nitrocefin is a chromogenic β-lactamase substrate that undergoes distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 872.0±65.0 °C at 760 mmHg |
| Melting Point | >99℃ |
| Molecular Formula | C21H16N4O8S2 |
| Molecular Weight | 516.504 |
| Flash Point | 481.2±34.3 °C |
| Exact Mass | 516.040955 |
| PSA | 231.89000 |
| LogP | 1.04 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.749 |
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41906-86-9 |
| Literature: Lee, Mijoon; Hesek, Dusan; Mobashery, Shahriar Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 367 - 369 |
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41906-86-9 |
| Literature: Lee, Mijoon; Hesek, Dusan; Mobashery, Shahriar Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 367 - 369 |
| Precursor 1 | |
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| DownStream 0 | |