220851-29-6

220851-29-6 structure

Name: tert-Butyl 11-aminoundecanoate
Chemical Name: tert-butyl 11-aminoundecanoate
CAS Number: 220851-29-6
Molecular Formula: C₁₅H₃₁NO₂
Molecular Weight: 257.41200
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-10-24 19:25:56
Modify Date: 2024-01-12 20:28:45
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	tert-butyl 11-aminoundecanoate
Synonyms	MFCD31729305

Description	tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
References	[1]. Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.

Hazard Codes	C