di-O-methyldemethoxycurcumin

Names

[ CAS No. ]:
824951-60-2

[ Name ]:
di-O-methyldemethoxycurcumin

[Synonym ]:
dimethyl demethoxycurcumin
dimethyl DC

Biological Activity

[Description]:

Di-O-methyldemethoxycurcumin, a curcuminoid analog isolated from the medicinal plant Curcuma longa L., inhibits IL-6 production with an EC50 of 16.20 μg/mL. Anti-inflammatory and antioxidant properties[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[Target]

IL-6


[References]

[1]. Nuntana Aroonrerk, et al. Inhibitory effects of di-O-demethylcurcumin on interleukin-1β-induced interleukin-6 production from human gingival fibroblasts. J Dent Sci. 2012 Dec;7(14): 350-358.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H22O5

[ Molecular Weight ]:
366.40700

[ Exact Mass ]:
366.14700

[ PSA ]:
61.83000

[ LogP ]:
3.96730

Related Compounds