Xanthohumol I

Names

[ CAS No. ]:
688360-06-7

[ Name ]:
Xanthohumol I

Biological Activity

[Description]:

Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE

BChE


[References]

[1]. Orhan IE, et al. Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives. Phytomedicine. 2018 Mar 15;42:25-33.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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