IKK-IN-3

Names

[ CAS No. ]:
615528-53-5

[ Name ]:
IKK-IN-3

Biological Activity

[Description]:

IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> IKK
Research Areas >> Inflammation/Immunology

[References]

[1]. Kempson J , et al. Novel tricyclic inhibitors of IkappaB kinase. J Med Chem. 2009;52(7):1994‐2005.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H17N5S

[ Molecular Weight ]:
323.42

Related Compounds