CD80-IN-3

Names

[ CAS No. ]:
486449-65-4

[ Name ]:
CD80-IN-3

Biological Activity

[Description]:

CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11(12):1651-8.

Chemical & Physical Properties

[ Density]:
1.536g/cm3

[ Boiling Point ]:
594.3ºC at 760 mmHg

[ Molecular Formula ]:
C17H10FN3O3

[ Molecular Weight ]:
323.27800

[ Flash Point ]:
313.2ºC

[ Exact Mass ]:
323.07100

[ PSA ]:
87.98000

[ LogP ]:
2.70430

[ Index of Refraction ]:
1.725

Related Compounds