4-Methoxyamphetamine (hydrochloride) (exempt preparation)

Names

[ CAS No. ]:
3706-26-1

[ Name ]:
4-Methoxyamphetamine (hydrochloride) (exempt preparation)

[Synonym ]:
1-(4-Methoxyphenyl)-2-propanamine hydrochloride (1:1)
Benzeneethanamine, 4-methoxy-α-methyl-, hydrochloride (1:1)
Benzeneethanamine, 4-methoxy-α-methyl-, hydrochloride (9CI)
4-methoxyamphetamine hydrochloride
p-Methoxyamphetamine hydrochloride
Phenethylamine, 4-methoxy-α-methyl-, hydrochloride

Chemical & Physical Properties

[ Density]:
0.99g/cm3

[ Boiling Point ]:
258.2ºC at 760mmHg

[ Molecular Formula ]:
C10H16ClNO

[ Molecular Weight ]:
201.693

[ Flash Point ]:
107.5ºC

[ Exact Mass ]:
201.092041

[ PSA ]:
35.25000

[ LogP ]:
3.08720

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SH8124400
CHEMICAL NAME :
Phenethylamine, p-methoxy-alpha-methyl-, hydrochloride
CAS REGISTRY NUMBER :
3706-26-1
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H15-N-O.Cl-H
MOLECULAR WEIGHT :
201.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,150,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
91 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 55,466,1959 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1300 mg/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,301,1996
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
650 mg/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
REFERENCE :
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 10,301,1996

Safety Information

[ HS Code ]:
2922299090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%