CB1-IN-2

Names

[ CAS No. ]:
2527805-39-4

[ Name ]:
CB1-IN-2

Biological Activity

[Description]:

CB1-IN-2 (Compound 4g) is a selective CB1 inhibitor with an IC50 of 0.644 μM. CB1-IN-2 can penetrates BBB and might cause CNS side effect similar with Rimonabant[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[Target]

CB1:0.644 μM (IC50)


[References]

[1]. Tsai SE, et al. Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues. Bioorg Chem. 2020 Nov;104:104299.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H19Cl2N5O

[ Molecular Weight ]:
380.27

Related Compounds