PI3K/mTOR Inhibitor-5

Names

[ Name ]:
PI3K/mTOR Inhibitor-5

Biological Activity

[Description]:

PI3K/mTOR Inhibitor-5 (compound 19a) is a potent and dual PI3K and mTOR inhibitor, with IC50 values of 86.9 nM and 14.6 nM, respectively[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[Target]

IC50: 86.9 nM (PI3K), 14.6 nM (mTOR)[1]

[References]

[1]. Wu TT, Guo QQ, Chen ZL, et al. Design, synthesis and bioevaluation of novel substituted triazines as potential dual PI3K/mTOR inhibitors. Eur J Med Chem. 2020;204:112637.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₀N₁₀O₃

[ Molecular Weight ]:
612.73

Related Compounds

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