Hypoxanthine-13C,15N2

Names

[ CAS No. ]:
244769-71-9

[ Name ]:
Hypoxanthine-13C,15N2

[Synonym ]:
6-Hydroxy-1H-purine-13C,15N2
6-Oxopurine-13C,15N2
1,9-Dihydro-6H-purin-6-one-13C,15N2
3H-Purin-6-ol-13C,15N2
Hypoxanthine Enol-13C,15N2
6-Hydroxypurine-13C,15N2

Biological Activity

[Description]:

Hypoxanthine-13C,15N2 is a 15N-labeled and 13C-labled Furaltadone. Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-246.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-246.

Chemical & Physical Properties

[ Molecular Formula ]:
C413CH4N215N2O

[ Molecular Weight ]:
139.09

[ Exact Mass ]:
139.03600

[ PSA ]:
74.69000

[ LogP ]:
0.05850

Related Compounds