PPARγ agonist 4

Names

[ CAS No. ]:
2380227-06-3

[ Name ]:
PPARγ agonist 4

Biological Activity

[Description]:

PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

[References]

[1]. Schoepf AM, et al. Overcoming imatinib resistance in chronic myelogenous leukemia cells using non-cytotoxic cell death modulators. Eur J Med Chem. 2020 Jan 1;185:111748.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H22FN3O

[ Molecular Weight ]:
387.45

Related Compounds

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