Pirepemat fumarate
Names
[ CAS No. ]:
2251806-70-7
[ Name ]:
Pirepemat fumarate
Biological Activity
[Description]:
Pirepemat (IRL752) fumarate is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat fumarate is used for the study of Parkinson's disease[1][2].
[Related Catalog]:
[In Vitro]
IRL752 fumarate displays its highest in vitro affinities for 5-HT and NA-related targets[2].
[In Vivo]
IRL752 (3.7-100 µmol/kg, s.c.) fumarate has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reverses deficits resulting from hypomonoaminergic function[2]. Animal Model: Normal rats[2] Dosage: 3.7-100 µmol/kg Administration: S.c., 30 min prior to testing Result: Induced dose-dependent and regio-selective alterations in brain monoamine transmission indices and gene expression.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C15H17F2NO5
[ Molecular Weight ]:
329.30