JMI-346

Names

[ CAS No. ]:
2091841-46-0

[ Name ]:
JMI-346

Biological Activity

[Description]:

JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Uddin A, et al. Identification and structure-activity relationship (SAR) studies of carvacrol derivatives as potential anti-malarial against Plasmodium falciparum falcipain-2 protease. Bioorg Chem. 2020 Oct;103:104142.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₀N₄O₂

[ Molecular Weight ]:
336.39

Related Compounds

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