IRL-3630

Names

[ CAS No. ]:
173189-01-0

[ Name ]:
IRL-3630

[Synonym ]:
unii-vun0h9v085
irl-3630
irl-3461

Biological Activity

[Description]:

IRL-3630 (Compound 3) is an ETA/ETB antagonist (Ki: 1.9 and 1.2 nM)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor

[References]

[1]. Sakaki J, et al. Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2247-52.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₄₀N₄O₆S

[ Molecular Weight ]:
596.73700

[ Exact Mass ]:
596.26700

[ PSA ]:
153.25000

[ LogP ]:
6.34060

Related Compounds

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