173189-01-0

173189-01-0 structure

Name: IRL-3630
Chemical Name: N-[(2R)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-butylsulfonylamino]-3-[4-(1,2-oxazol-5-yl)phenyl]-1-oxopropan-2-yl]-N,3,5-trimethylbenzamide
CAS Number: 173189-01-0
Molecular Formula: C₃₁H₄₀N₄O₆S
Molecular Weight: 596.73700
Catalog: Signaling Pathways GPCR/G Protein Endothelin Receptor
Create Date: 2017-12-21 16:58:25
Modify Date: 2025-09-02 11:20:25
IRL-3630 (Compound 3) is an ETA/ETB antagonist (Ki: 1.9 and 1.2 nM)[1].

Name	N-[(2R)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-butylsulfonylamino]-3-[4-(1,2-oxazol-5-yl)phenyl]-1-oxopropan-2-yl]-N,3,5-trimethylbenzamide
Synonyms	unii-vun0h9v085 irl-3630 irl-3461

Description	IRL-3630 (Compound 3) is an ETA/ETB antagonist (Ki: 1.9 and 1.2 nM)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor
References	[1]. Sakaki J, et al. Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2247-52.