Duocarmycin GA

Names

[ CAS No. ]:
1613286-59-1

[ Name ]:
Duocarmycin GA

Biological Activity

[Description]:

Duocarmycin GA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-drug resistant cell lines.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

[References]

[1]. Searcey M. Duocarmycins--natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25ClN4O3

[ Molecular Weight ]:
476.95

Related Compounds

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