4-Amino-PPHT

Names

[ CAS No. ]:
129298-03-9

[ Name ]:
4-Amino-PPHT

[Synonym ]:
(RS)-2-[N-(p-aminophenethyl)-N-propylamino]-5-hydroxytetralin
2-[N-phenylethyl-N-propyl]amino-5-hydroxytetralin

Biological Activity

[Description]:

4-Amino-PPHT (Compound 9a) is a PPHT derivative that selectively binds to dopamine D-2 receptors with a Ki value of 6.8 nM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Bakthavachalam V, et al. Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands. J Med Chem. 1991 Nov;34(11):3235-41.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H28N2O

[ Molecular Weight ]:
324.46000

[ Exact Mass ]:
324.22000

[ PSA ]:
49.49000

[ LogP ]:
4.36760

Related Compounds

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