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Camstatin TFA

Names

[ CAS No. ]:
1002295-95-5

[ Name ]:
Camstatin TFA

Biological Activity

[Description]:

Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Neurological Disease

[In Vitro]

Camstatin is a synthetic peptide encompassing the minimal IQ motif of PEP-19 that binds apoCaM and inhibits the activities of the CaM-dependent enzymes neuronal nitric oxide synthase (nNOS) and CaM-kinase II[1].

[References]

[1]. J Bradley Dickerson, et al. The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19. Brain Res. 2006 May 30;1092(1):16-27.

Chemical & Physical Properties

[ Molecular Formula ]:
C122H203N39O34

[ Molecular Weight ]:
2760.16

[ Storage condition ]:
-20°C

Related Compounds