nicosulfuron [ANSI]

Names

[ CAS No. ]:
111991-09-4

[ Name ]:
nicosulfuron [ANSI]

[Synonym ]:
2-{[(4,6-Dimethoxy-2-pyrimidinyl)carbamoyl]sulfamoyl}-N,N-dimethylnicotinamide
2-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-N,N-dimethylnicotinamide
N'-(4,6-Dimethoxy-2-pyrimidinyl)-N-{[3-(dimethylcarbamoyl)-2-pyridinyl]sulfonyl}carbamimidic acid
nicosulfuron [ANSI]
3-Pyridinecarboxamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-
1-(4,6-Dimethoxypyrimidin-2-yl)-3-(3-dimethylcarbamoyl-2-pyridylsulfonyl)urea
2-{[(4,6-Dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide
MFCD00203303
DPX V9360
EINECS 244-666-2
2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide
T6N CNJ DO1 FO1 BMVMSW- BT6NJ CVN1&1
2-[[[[(4,6-Dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide
2-{[(4,6-Dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylnicotinamide
3-Pyridinecarboxamide, 2-[[[(Z)-[(4,6-dimethoxy-2-pyrimidinyl)imino]hydroxymethyl]amino]sulfonyl]-N,N-dimethyl-
Nicosulfuron

Biological Activity

[Description]:

Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Louis Carles, et al. Nicosulfuron Degradation by an Ascomycete Fungus Isolated From Submerged Alnus Leaf Litter. Front Microbiol. 2018 Dec 19;9:3167.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
719.1±70.0 °C at 760 mmHg

[ Melting Point ]:
141-144°C

[ Molecular Formula ]:
C₁₅H₁₈N₆O₆S

[ Molecular Weight ]:
410.405

[ Flash Point ]:
388.7±35.7 °C

[ Exact Mass ]:
410.100861

[ PSA ]:
161.09000

[ LogP ]:
-2.09

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.640

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US4615000

CHEMICAL NAME :: 3-Pyridinecarboxamide, 2-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)ami no)sulfonyl)- N,N-dimethyl-

CAS REGISTRY NUMBER :: 111991-09-4

LAST UPDATED :: 199109

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H18-N6-O6-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C219,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C219,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >2250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C219,1991

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H410

[ Precautionary Statements ]:
P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S24/25-S26

[ RIDADR ]:
UN 3077 9 / PGIII

[ RTECS ]:
US4615000

[ HS Code ]:
2935009013

Customs

[ HS Code ]: 2935009013

[ Summary ]:
2935009013 methyl 2-((n-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)methyl)benzoate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

Articles

Targeted three-dimensional liquid chromatography: A versatile tool for quantitative trace analysis in complex matrices

J. Chromatogr. A. 1217(49) , 7648-60, (2010)

Targeted multidimensional liquid chromatography (MDLC), commonly referred to as ‘coupled-column’ or ‘heartcutting’, has been used extensively since the 1970s for analysis of low concentration constitu...

Influence of soil biochar aging on sorption of the herbicides MCPA, nicosulfuron, terbuthylazine, indaziflam, and fluoroethyldiaminotriazine.

J. Agric. Food Chem. 62(45) , 10855-60, (2014)

Sorption of four herbicides and a metabolite of indaziflam on a fresh macadamia nut biochar and biochars aged one or two years in soil was characterized. On fresh biochar, the sorption was terbuthylaz...

The study of the interactions between heavy metals with sulfonylurea herbicides using ACE.

J. Chromatogr. Sci. 47(2) , 116-20, (2009)

The affinity capillary electrophoresis method was used in the study of interactions between heavy metals (Pb, Mn, La, Cd, and Ni) and the sulfonylurea herbicides (thifensulfuron, nicosulfuron and sulf...