4-Hydrazinylbenzoic acid

Names

[ CAS No. ]:
619-67-0

[ Name ]:
4-Hydrazinylbenzoic acid

[Synonym ]:
EINECS 210-609-5
Benzoic acid, 4-hydrazinyl-
4-hydrazinylbenzoic acid
MFCD00007581
4-Hydrazinobenzoic acid
4-Hydrazinobenzoicacid
Deferasirox Impurity 1

Biological Activity

[Description]:

4-Hydrazinobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
377.2±25.0 °C at 760 mmHg

[ Melting Point ]:
218 °C (dec.)(lit.)

[ Molecular Formula ]:
C₇H₈N₂O₂

[ Molecular Weight ]:
152.15

[ Flash Point ]:
181.9±23.2 °C

[ Exact Mass ]:
152.058578

[ PSA ]:
75.35000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.694

[ Stability ]:
Stable. Combustible. Incompatible with strong acids, strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH1700000

CHEMICAL NAME :: Benzoic acid, p-hydrazino-

CAS REGISTRY NUMBER :: 619-67-0

BEILSTEIN REFERENCE NO. :: 0387378

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H8-N2-O2

MOLECULAR WEIGHT :: 152.17

WISWESSER LINE NOTATION :: ZMR DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 137 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - breast

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 3 umol/plate

REFERENCE :: ZLUFAR Zeitschrift fuer Lebensmittel-Untersuchung und-Forschung. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.86- 1943- Volume(issue)/page/year: 183,85,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
DH1700000

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Strategies for optimizing the performance of carbazole thiophene appended unsymmetrical squaraine dyes for dye-sensitized solar cells.

Phys. Chem. Chem. Phys. 17 , 23095-103, (2015)

Unsymmetrical squaraine dyes (CTSQ-1 and CTSQ-2) with carbazole thiophene donor units were synthesized, characterized and used as sensitizers in dye-sensitized solar cells (DSSCs). These squaraines ex...

Aortic rupture and aortic smooth muscle tumors in mice. Induction by p-hydrazinobenzoic acid hydrochloride of the cultivated mushroom Agaricus bisporus.

Lab. Invest. 57(1) , 78-85, (1987)

p-Hydrazinobenzoic acid (HBA), an ingredient of the cultivated mushroom Agaricus bisporus, was given in hydrochloride form at a dosage of 0.125% in drinking water for life to randomly bred Swiss mice....

Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus.

Free Radic. Res. 40(1) , 31-9, (2006)

4-Hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus, is carcinogenic to rodents. To clarify the mechanism of carcinogenesis, we investigated DNA damage by 4-hydrazinobenzoic acid usin...