Potassium guaiacolsulfonate hemihydrate

Names

[ Name ]:
Potassium guaiacolsulfonate hemihydrate

[Synonym ]:
POTASSIUMGUAIACOLSULFONATE,USP
Potassium hydroxymethoxybenzenesulfonate hemihydrate
hydroxymethoxy-benzenesulfonicacimonopotassiumsalt
PotassiuM guaiacolsulfonate heMihydrate API
PATSSIUMGUAIACOLSULFONATE
POTASSIUM GUAIACOLSULFONATE HYDRATE
Potassium 4-hydroxy-3-methoxybenzenesulfonate hydrate (2:2:1)
Benzenesulfonic acid, 4-hydroxy-3-methoxy-, potassium salt, hydrate (2:2:1)
PotassiuM Guaiacolsulfonate,HeMihydrate,USP

Biological Activity

[Description]:

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other drugs[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Potassium guaiacolsulfonate hemihydrate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up[1].

[References]

[1]. Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061.

[2]. Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83(5):1601-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₈O₅S_.1/₂H₂O_.K

[ Molecular Weight ]:
502.597

[ Exact Mass ]:
501.940826

[ PSA ]:
199.31000

[ LogP ]:
2.70710

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2909500000

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%