Diammonium phosphate

Names

[ Name ]:
Diammonium phosphate

[Synonym ]:
Diammonium hydrogen phosphate
Diammonium hydrogenphosphate
MFCD00010891
diazanium,hydrogen phosphate
EINECS 231-987-8
Ammonium hydrogen phosphate (2:1:1)

Biological Activity

[Description]:

Diammonium phosphate is a neutral and efficient catalyst in 1,8‐Dioxo‐octahydroxanthene derivatives synthesis. Diammonium phosphate can be used as an excipient, such as diuretic, buffer, effervescent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Darviche F, et al. Diammonium hydrogen phosphate as a neutral and efficient catalyst for synthesis of 1, 8‐dioxo‐octahydroxanthene derivatives in aqueous media[J]. Synthetic Communications, 2007, 37(7): 1059-1066.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
1.203 g/mL at 25 °C

[ Boiling Point ]:
158ºC at 760 mmHg

[ Melting Point ]:
155 °C (dec.)(lit.)

[ Molecular Formula ]:
H₉N₂O₄P

[ Molecular Weight ]:
132.06

[ Exact Mass ]:
132.029999

[ PSA ]:
94.05000

[ Index of Refraction ]:
1.53

[ Stability ]:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

[ Water Solubility ]:
58 g/ 100mL (10 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2919900090

Customs

[ HS Code ]: 2919900090

[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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