Sodium 2-octadecylfumarate

Names

[ Name ]:
Sodium 2-octadecylfumarate

[Synonym ]:
2-Butenedioic acid, monooctadecyl ester, sodium salt, (2E)- (1:1)
Fumaric Acid Stearyl Ester Sodium Salt
Sodium (2E)-4-(octadecyloxy)-4-oxobut-2-enoate
(E)-2-Butenedioic acid monooctadecyl ester sodium salt Sodium octadecyl fumarate
Sodium (2E)-4-(octadecyloxy)-4-oxo-2-butenoate
Sodium Octadecyl Fumarate
Fumaric Acid Octadecyl Ester Sodium Salt
(E)-2-Butenedioic acid monooctadecyl ester sodium salt,Sodium octadecyl fumarate
Sodium stearyl fumarate
EINECS 223-781-1

Biological Activity

[Description]:

Sodium stearyl fumarate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Boiling Point ]:
483.4ºC at 760mmHg

[ Molecular Formula ]:
C₂₂H₃₉NaO₄

[ Molecular Weight ]:
390.53

[ Flash Point ]:
153.5ºC

[ Exact Mass ]:
390.274597

[ PSA ]:
77.43000

[ LogP ]:
5.39890

[ Water Solubility ]:
Practically insoluble in water, slightly soluble in methanol, practically insoluble in acetone and in anhydrous ethanol.

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2917190090

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

[The effect of two lubricants (magnesium stearate and pruv) in the formation of tablets of four anti-ulcer agents/ by means of direct compression].

Pharm. Acta Helv. 67(2) , 50-6, (1992)

In this research we study the influence of two lubricants-Magnesium Stearate and Pruv--on the tablets elaboration of Cimetidine, Ranitidine, Famotidine and Pirenzepine by direct compression. The prese...