Meloxicam
Names
[ CAS No. ]:
71125-38-7
[ Name ]:
Meloxicam
[Synonym ]:
Meloxicam
Metacam
Parocin
2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide
4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboximidic acid 1,1-dioxide
Meloxciam
4-hydroxy-2-méthyl-N-(5-méthyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxyde
2H-1,2-Benzothiazine-3-carboximidic acid, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide
Movatec
structure was taken from Chemical Abstracts Index Guide, number
4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
meloxicam (tautomer)
MOBIC
Mobicox
MFCD11046047
Movalis
MOBEC
Biological Activity
[Description]:
[Related Catalog]:
[Target]
COX-2:0.49 μM (IC50)
COX-1:36.6 μM (IC50)
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
581.3±60.0 °C at 760 mmHg
[ Melting Point ]:
255ºC
[ Molecular Formula ]:
C14H13N3O4S2
[ Molecular Weight ]:
351.401
[ Flash Point ]:
305.4±32.9 °C
[ Exact Mass ]:
351.034760
[ PSA ]:
136.22000
[ LogP ]:
3.35
[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C
[ Index of Refraction ]:
1.735
[ Water Solubility ]:
DMSO: soluble
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
26
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
DL0702000
[ Packaging Group ]:
III
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Vet. Sci. 14(1) , 7-14, (2013)
An improved method to determine meloxicam (MEL) concentrations in koala plasma using reversed phase high performance liquid chromatography equipped with a photo diode array detector was developed and ...
Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses.Am. J. Vet. Res. 75(7) , 668-79, (2014)
To compare the effects of 2 NSAIDs (phenylbutazone and meloxicam) on renal function in horses.9 Thoroughbred or Standardbred mares (mean ± SD age, 5.22 ± 1.09 years [range, 2 to 12 years]; mean body w...
Meloxicam-loaded nanocapsules have antinociceptive and antiedematogenic effects in acute models of nociceptionLife Sci. 115(1-2) , 36-43, (2014)
Aims The development of new treatments for inflammation and pain continues to be of high interest, since long-acting effect is critical for patients. The present study investigated whether the polymer...