2-Acetlimidazole

Names

[ Name ]:
2-Acetlimidazole

[Synonym ]:
2-Formylimidazole
1H-2-imidazolecarbaldehyde
imidazole 2-carboxaldeyde
2-FORMAYLIMIDAZOLE
2-imidazolylcarboxaldehyde
1H-Imidazole-2-carboxaldehyde
2-1H-imidazolcarbaldehyde
Imidazole-2-carbaldehyde
1H-Imidazole-2-carbaldehyde
Imidazole-2-carboxaldehyde
2-IMIDAZOLECARBOXALDEHYDE
MFCD00003544
2-Formyl-1H-imidazole
2-AcetliMidazole
IMIDAZOL-2-CARBALDEHYDE
Imidazole-2-carboxal

Biological Activity

[Description]:

1H-Imidazole-2-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Imidazole-2-carboxaldehyde 是一种新型蛋白酪氨酸磷酸酶 1B (PTP1B) 抑制剂，在抑制 2 型糖尿病方面具有重要应用。通过与氨基酸β-丙氨酸和2-氨基苯甲酸进行缩合反应，用于制备含三齿席夫碱羧酸盐的配体。它还参与了咪唑导向的醛亚胺烯丙基化研究。

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
296.5±23.0 °C at 760 mmHg

[ Melting Point ]:
209 °C (dec.)(lit.)

[ Molecular Formula ]:
C₄H₄N₂O

[ Molecular Weight ]:
96.09

[ Flash Point ]:
137.5±29.0 °C

[ Exact Mass ]:
96.032364

[ PSA ]:
45.75000

[ LogP ]:
-0.33

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S3

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine.

Pharm. Res. 32 , 2625-35, (2015)

An unknown UV 280 nm absorbing peak was observed by SEC for protein stability samples formulated in L-histidine during a stress stability study. Understanding the source would enhance the confidence i...

Mixed ligand copper(II) complexes of 1,10-phenanthroline with tridentate phenolate/pyridyl/(benz)imidazolyl Schiff base ligands: covalent vs non-covalent DNA binding, DNA cleavage and cytotoxicity.

J. Inorg. Biochem. 140 , 255-68, (2014)

A series of copper(II) complexes of the types [Cu(L)(phen)](ClO4) 1-2, where HL is a tridentate ligand with two nitrogen and one oxygen donor atoms (2NO) such as 2-(2-(1H-benzimidazol-2-yl)ethyliminom...

Helical-chain copper(II) complexes and a cyclic tetranuclear copper(II) complex with single syn-anti carboxylate bridges and ferromagnetic exchange interactions.

Inorg. Chem. 39(13) , 2882-90, (2000)

Tridentate Schiff-base carboxylate-containing ligands, derived from the condensation of 2-imidazolecarboxaldehyde with the amino acids beta-alanine (H2L1) and 2-aminobenzoic acid (H2L5) and the conden...