2,3-dinitrotoluene

Names

[ CAS No. ]:
602-01-7

[ Name ]:
2,3-dinitrotoluene

[Synonym ]:
2,3-Dinitrotoluol
Benzene,1-methyl-2,3-dinitro
2,3-DNT
1,3-dinitrotoluene
Toluene,2,3-dinitro
EINECS 210-013-5
2,3-DINITROTOLUENE
MFCD00007178

Chemical & Physical Properties

[ Density]:
1.407 g/cm3

[ Boiling Point ]:
331.5ºC at 760 mmHg

[ Melting Point ]:
59-61 °C(lit.)

[ Molecular Formula ]:
C₇H₆N₂O₄

[ Molecular Weight ]:
182.13400

[ Flash Point ]:
170.2ºC

[ Exact Mass ]:
182.03300

[ PSA ]:
91.64000

[ LogP ]:
2.85780

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT1400000

CHEMICAL NAME :: Toluene, 2,3-dinitro-

CAS REGISTRY NUMBER :: 602-01-7

BEILSTEIN REFERENCE NO. :: 2212428

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C7-H6-N2-O4

MOLECULAR WEIGHT :: 182.15

WISWESSER LINE NOTATION :: WNR B1 FNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 911 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1072 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - rat Liver

REFERENCE :: SinJF# Personal Communication from J.F. Sina, Merck Institute for Therapeutic Research, West Point, PA 19486, Oct. 26, 1982 Volume(issue)/page/year: 26OCT1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 2,3-DINITROTOLUENE-air:10H CA TWA 1.5 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331-H341-H350-H361f-H373-H410

[ Precautionary Statements ]:
P201-P261-P273-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;

[ Risk Phrases ]:
R45

[ Safety Phrases ]:
S53-S45-S60-S61

[ RIDADR ]:
UN 3454 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
XT1400000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Click to get detail synthetic route

Articles

Evaluation of the dependence of aqueous solubility of nitro compounds on temperature and salinity: a COSMO-RS simulation.

Chemosphere 83(3) , 287-94, (2011)

The solubility in pure and saline water at various temperatures was calculated for selected nitro compounds (nitrobenzene, 1,3,5-trinitrobenzene, 2-nitrotoluene, 3-nitrotoluene, 4-nitrotoluene, 2,4-di...

Solid-phase microextraction versus single-drop microextraction for the analysis of nitroaromatic explosives in water samples.

J. Chromatogr. A. 938(1-2) , 113-20, (2001)

This paper compares solid-phase microextraction (SPME) with a recently developed extraction method called single-drop microextraction (SDME) for the analysis of nitroaromatic explosives in water sampl...

TNT and nitroaromatic compounds are chemoattractants for Burkholderia cepacia R34 and Burkholderia sp. strain DNT.

Appl. Microbiol. Biotechnol. 69(3) , 321-5, (2005)

Nitroaromatic compounds are toxic and potential carcinogens. In this study, a drop assay was used to detect chemotaxis toward nitroaromatic compounds for wild-type Burkholderia cepacia R34, wild-type ...