Methylnitronitrosoguanidine

Names

[ CAS No. ]:
70-25-7

[ Name ]:
Methylnitronitrosoguanidine

[Synonym ]:
guanidine, N-methyl-N''-nitro-N-nitroso-
1-Methyl-3-nitro-1-nitrosoguanidine
MFCD00007034
Guanidine, N-methyl-N'-nitro-N-nitroso-
Methylnitronitrosoguanidine
N-methyl-N'-nitro-N-nitrosoguanidine
1-methyl-2-nitro-1-nitrosoguanidine
EINECS 200-730-1
MNNG

Biological Activity

[Description]:

Methylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

[Target]

DNA Alkylator/Crosslinker[1]

[References]

[1]. Slapikoff SA, et al. Comparison of toxicity and mutagenicity of methylnitrosourea, methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines. Mutat Res. 1980 May;70(3):365-71.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
207.8±23.0 °C at 760 mmHg

[ Melting Point ]:
118°C (dec.)

[ Molecular Formula ]:
C₂H₅N₅O₃

[ Molecular Weight ]:
147.09

[ Flash Point ]:
79.5±22.6 °C

[ Exact Mass ]:
147.039246

[ PSA ]:
114.37000

[ LogP ]:
-0.79

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.641

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
Reacts violently

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R45;R20;R36/38;R51/53

[ Safety Phrases ]:
S53-S45-S61

[ RIDADR ]:
2926

[ RTECS ]:
MF4200000

[ Packaging Group ]:
II

[ Hazard Class ]:
4.1

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%