4-isopropoxybenzaldehyde

Names

[ Name ]:
4-isopropoxybenzaldehyde

[Synonym ]:
4-Isopropoxybenzaldehyde
p-isopropoxybenzaldehyde
p-isopropyloxy benzaldehyde
4-ISOPROPOXY-1-FORMYLBENZENE
4-iso-propyloxybenzaldehyde
MFCD00052357

Biological Activity

[Description]:

ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)

Research Areas >> Cancer

[Target]

IC50: 0.26 μM (ALDH1A3)[1]

[References]

[1]. Ibrahim AIM, et, al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

Chemical & Physical Properties

[ Density]:
1.036

[ Boiling Point ]:
108-110 °C (5 mmHg)

[ Molecular Formula ]:
C₁₀H₁₂O₂

[ Molecular Weight ]:
164.20100

[ Flash Point ]:
108-110°C/5mm

[ Exact Mass ]:
164.08400

[ PSA ]:
26.30000

[ LogP ]:
2.28630

[ Vapour Pressure ]:
0.00982mmHg at 25°C

[ Index of Refraction ]:
1.545-1.547

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ HS Code ]:
2912499000

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%