Alpinetin

Names

[ Name ]:
Alpinetin

[Synonym ]:
7-hydroxy-5-methoxy-2-phenyl-chroman-4-one
(2S)-7-Hydroxy-5-methoxy-2-phenyl-2,3-dihydro-4H-1-benzopyran-4-one
(S)-7-Hydroxy-5-methoxyflavanone
Alpinetin: 7-hydroxy-5-methoxy-2-phenylchroman-4-one
(2S)-7-Hydroxy-5-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
7-Hydroxy-5-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-
MFCD00238532
(S)-7-Hydroxy-5-methoxy-2-phenylchroman-4-one
7-Hydroxy-5-methoxy-2-phenyl-chroman-4-on
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-
Alpinetin

Biological Activity

[Description]:

Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Inflammation/Immunology

[Target]

PPAR-γ

[References]

[1]. Hu K, et al. Alpinetin inhibits LPS-induced inflammatory mediator response by activating PPAR-γ in THP-1-derived macrophages. Eur J Pharmacol. 2013 Dec 5;721(1-3):96-102.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
494.9±45.0 °C at 760 mmHg

[ Melting Point ]:
223-224ºC

[ Molecular Formula ]:
C₁₆H₁₄O₄

[ Molecular Weight ]:
270.280

[ Flash Point ]:
188.8±22.2 °C

[ Exact Mass ]:
270.089203

[ PSA ]:
55.76000

[ LogP ]:
3.71

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.612

Safety Information

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%