2',3'-Dideoxythymidine

Names

[ Name ]:
2',3'-Dideoxythymidine

[Synonym ]:
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
ddT & GM-CSF
Thymidine,2',3'-dideoxy
2'-3'-didehydro-2'-3'-dideoxythymidine
1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
MFCD00010570
2',3'-dideoxy-2',3'-didehydro-thymydine
D-3'-deoxythymidine
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
5-methyl-2',3'-dideoxyuridine
2',3'-dihydro-3'-deoxythymidine
3'-DEOXYTHYMIDINE
Dideoxythymidine
2',3'-Dideoxythymidine
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
155-156 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₄N₂O₄

[ Molecular Weight ]:
226.229

[ Exact Mass ]:
226.095352

[ PSA ]:
84.32000

[ LogP ]:
-0.76

[ Index of Refraction ]:
1.552

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

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PLoS ONE 10(4) , e0123460, (2015)

Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransfer...

Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.

Antimicrob. Agents Chemother. 58(9) , 5036-46, (2014)

Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant...

Cuboplexes: Topologically Active siRNA Delivery.

ACS Nano 9 , 10214-26, (2015)

RNAi technology is currently experiencing a revival due to remarkable improvements in efficacy and viability through oligonucleotide chemical manipulations and/or via their packaging into nanoscale ca...