Ibacitabine

Names

[ CAS No. ]:
611-53-0

[ Name ]:
Ibacitabine

[Synonym ]:
EINECS 210-269-8
MFCD00038063
4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodpyrimidin-2(1H)-on
4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-iodo-2(1H)-pyrimidinone
Cytidine, 2'-deoxy-5-iodo-
Ibacitabine
2'-Deoxy-5-iodocytidine
4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

Biological Activity

[Description]:

Ibacitabine, an antiviral compound, can be used for gene sequencing[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. A Serpentier-Daude, Contact dermatitis to topical antiviral drugs. Ann Dermatol Venereol. 2000 Feb;127(2):191-3.

Chemical & Physical Properties

[ Density]:
2.4±0.1 g/cm3

[ Boiling Point ]:
522.1±60.0 °C at 760 mmHg

[ Melting Point ]:
185 °C

[ Molecular Formula ]:
C₉H₁₂IN₃O₄

[ Molecular Weight ]:
353.114

[ Flash Point ]:
269.6±32.9 °C

[ Exact Mass ]:
352.987244

[ PSA ]:
110.60000

[ LogP ]:
-0.69

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.815

[ Storage condition ]:
Store at 0°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn,T

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
23-26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

In vitro sensitivity of macropodid herpesvirus 2 to selected anti-herpetic compounds.

J. Wildl. Dis. 32(1) , 117-20, (1996)

We tested the in vitro sensitivity of Macropodid Herpesvirus 2 to eight commonly used anti-herpetic compounds using plaque reduction tests, March and April, 1995. The virus was most susceptible to inh...

[Antiviral drugs].

Rev. Prat. 35(47) , 2867-71, (1985)

Carbocyclic analogues of 5-halocytosine nucleosides.

J. Med. Chem. 29(9) , 1720-5, (1986)

Carbocyclic analogues of 5-halocytosine nucleosides were prepared by direct halogenation of the carbocyclic analogues of cytidine, 2'-deoxycytidine, 3'-deoxycytidine, or ara-C. The 5-chloro and 5-brom...