Published date: 2020-12-18 22:54:27
CAS number: 480998-12-7
Name: MC-DOXHZN hydrochloride
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Purity: 98.0%
Stocking period: 3 Day
Stock: In Stock
Product Webpage: https://www.dcchemicals.com/product_show-DOXO-EMCH;_EMCH-Doxo.html
Detail Product Information:
Aldoxorubicin, also known as INNO-206 and Doxo-EMCH, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin with antineoplastic activity. INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, once located intracellularly, intercalates DNA, inhibits DNA synthesis, and induces apoptosis. Albumin tends to accumulate in solid tumors as a result of high metabolic turnover, rapid angiogenesis, hyervasculature, and impaired lymphatic drainage. Because of passive accumulation within tumors, this agent may improve the therapeutic effects of doxorubicin while minimizing systemic toxicity.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 28108
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Detail introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: DC Chemicals Limited
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Tony Cao
Product Detail: DOXO-EMCH; EMCH-Doxo
Name: Dayang Chem (Hangzhou) Co., Ltd.
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Ms Wang
Product Detail: AIdoxorubicin Hydrochloride
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2021-07-26 AIdoxorubicin Hydrochloride
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