Published date: 2024-07-17 15:06:34
CAS number: 199735-88-1
Name: CADD522
Price:
$400.0/100mg
$800.0/250mg
$1600.0/1g
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-CADD522.html
Detail Product Information:
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 treatment resulted in significant growth inhibition, clonogenic survival, tumorsphere formation, and invasion of breast cancer cells. CADD522 negatively regulated transcription of RUNX2 target genes such as matrix metalloproteinase-13, vascular endothelial growth factor and glucose transporter-1, but upregulated RUNX2 expression by increasing RUNX2 stability. CADD522 reduced RUNX2-mediated increases in glucose uptake and decreased the level of CBF-β and RUNX2 phosphorylation at the S451 residue.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34963
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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Foreign Trade % of Salers:
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Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$400.0/100mg
$800.0/250mg
$1600.0/1g
Contact: Yang
Product Detail: CADD522
Name: DC Chemicals Limited
Area: China
Price:
$400.0/100mg
$800.0/250mg
$1600.0/1g
Contact: Tony Cao
Product Detail: CADD522
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$400.0/100mg
$800.0/250mg
$1600.0/1g
Contact: Tony Lai
Product Detail: CADD522
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