Published date: 2024-07-17 15:06:47
CAS number: 1146594-87-7
Name: JNJ-40418677
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-JNJ-40418677.html
Detail Product Information:
JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting processing of Notch. In human neuroblastoma cells and rat primary neuronal cultures, JNJ-40418677 blocked secretion of Aβb42 (IC50 = 20 nM), with no affects on total Ab concentration, Notch signaling or COX activity. In vivo experiments showed that JNJ-40418677 dose dependently inhibited Aβ42 accumulation in the brain while promoting an increase in Aβ38.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34963
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Yang
Product Detail: JNJ-40418677
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Tony Lai
Product Detail: JNJ-40418677
Name: DC Chemicals Limited
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Tony Cao
Product Detail: JNJ-40418677
Name: Dayang Chem (Hangzhou) Co., Ltd.
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Ms Wang
Product Detail: 2-(S)-(3,5-Bis(4-(trifluoromethyl)phenyl)phenyl)-4-methylpentanoic acid
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2024-07-15 JNJ-40418677
2022-11-29 JNJ-40418677
2021-07-26 2-(S)-(3,5-Bis(4-(trifluoromethyl)phenyl)phenyl)-4-methylpentanoic acid
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