2,6-Diisopropylaniline
Names
[ CAS No. ]:
24544-04-5
[ Name ]:
2,6-Diisopropylaniline
[Synonym ]:
2,5-DIHYDRO-5-OXO-1-(3-TRIFLUOROMETHYLPHENYL)-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID DIMETHYLAMIDE
2,6-Diisopropylaniline (DIPA)
Aniline,2,6-diisopropyl
EINECS 246-305-4
2,6-Dilsopropylaniline
2,6-bis(1-methylethyl)aniline
2,6-Diisopropyl-phenylamine
2,6-bis(1-methylethyl)benzenamine
2,6-DIISOPROPYLPHENYLAMINE
MFCD00008887
2,6-(i-Pr)2PhNH2
2,6-di(propan-2-yl)aniline
(2,6-iPr2C6H3)NH2
2,6-Diisopropylaniline
Benzenamine,2,6-bis(1-methylethyl)
2,6-di-i-propylaniline
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
257.3±9.0 °C at 760 mmHg
[ Melting Point ]:
−45 °C(lit.)
[ Molecular Formula ]:
C12H19N
[ Molecular Weight ]:
177.29
[ Flash Point ]:
123.9±0.0 °C
[ Exact Mass ]:
177.151749
[ PSA ]:
26.02000
[ LogP ]:
3.61
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.526
[ Water Solubility ]:
<0.20 g/L
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX4025000
- CHEMICAL NAME :
- Aniline, 2,6-diisopropyl-
- CAS REGISTRY NUMBER :
- 24544-04-5
- BEILSTEIN REFERENCE NO. :
- 2208763
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H19-N
- MOLECULAR WEIGHT :
- 177.32
- WISWESSER LINE NOTATION :
- 1Y1&R BZ CY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3204 mg/kg
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in bone marrow (not otherwise specified) Blood - changes in spleen
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 3,285,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4005 mg/kg/5D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 3,285,1983
Safety Information
[ Hazard Statements ]:
H412
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S61-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
BX4025000
[ HS Code ]:
29214980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Dalton Trans. 44(16) , 7230-41, (2015)
The 2-(2′-aniline)-6-imine-pyridines, 2-(C6H4-2′-NH2)-6-(CMe=NAr)C5H3N (Ar = 4-i-PrC6H4 (HL1a), 2,6-i-Pr2C6H3 (HL1b)), have been synthesised via sequential Stille cross-coupling, deprotection and cond...
O,N,N-pincer ligand effects on oxidatively induced carbon-chlorine coupling reactions at palladium.Dalton Trans. 44(13) , 6040-51, (2015)
The syntheses of two families of sterically tuneable O,N,N pro-ligands are reported, namely the 2-(phenyl-2'-ol)-6-imine-pyridines, 2-(C6H4-2'-OH),6-(CMe=NAr)C5H3N [Ar = 4-i-PrC6H4 (HL1(a)), 2,6-i-Pr2...
Rigid NON- and NSN-ligand complexes of tetravalent and trivalent uranium: comparison of U-OAr2 and U-SAr2 bonding.Dalton Trans. 41(26) , 8175-89, (2012)
A rigid NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene (H(2)[TXA(2)], 1) was prepared by palladium-catalyzed coupling of 2,6-diisopropylaniline with 4,...