LL-37 FKR trifluoroacetate salt

Names

[ CAS No. ]:
913736-94-4

[ Name ]:
LL-37 FKR trifluoroacetate salt

[Synonym ]:
L-Serine, L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-L-a rginyl-L-threonyl-L-α-glutamyl-
L-Phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-t hreonyl-L-α-glutamyl-L-serine

Biological Activity

[Description]:

LL-37 FKR is the C-terminal fragment of LL-37. LL-37 FKR plays an important role in antibacterial performance[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Sigurdardottir T, et al. In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37. Antimicrob Agents Chemother. 2006 Sep;50(9):2983-9.  

[2]. Ringstad L, et al. Effects of single amino acid substitutions on peptide interaction with lipid membranes and bacteria–variants of GKE21, an internal sequence from human LL-37[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2010, 354(1-3): 65-71.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C118H199N37O30

[ Molecular Weight ]:
2616.07

[ Exact Mass ]:
2614.518311

[ LogP ]:
-2.39

[ Index of Refraction ]:
1.650

Related Compounds