LL-37 GKE trifluoroacetate salt

Names

[ CAS No. ]:
913736-92-2

[ Name ]:
LL-37 GKE trifluoroacetate salt

[Synonym ]:
Glycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucy l-L-valyl-L-prolyl-L-arginine
L-Arginine, glycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparag inyl-L-leucyl-L-valyl-L-prolyl-

Biological Activity

[Description]:

LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Sigurdardottir T, et al. In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37. Antimicrob Agents Chemother. 2006 Sep;50(9):2983-9.  

[2]. Ringstad L, et al. Effects of single amino acid substitutions on peptide interaction with lipid membranes and bacteria–variants of GKE21, an internal sequence from human LL-37[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2010, 354(1-3): 65-71.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C119H202N38O28

[ Molecular Weight ]:
2613.11

[ Exact Mass ]:
2611.555176

[ LogP ]:
-2.41

[ Index of Refraction ]:
1.647

Related Compounds