(Tyr8)-Substance P

Names

[ CAS No. ]:
55614-10-3

[ Name ]:
(Tyr8)-Substance P

[Synonym ]:
[Tyr8 ]-substance P
substance PTyr8
L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Tyr-Gly-L-Leu-L-Met-NH2
RPKPQQFYGLM-NH2

Biological Activity

[Description]:

[Tyr8]-Substance P is an active peptide. [Tyr8]-Substance P can be used for the research of various biochemical[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

[Tyr8]-Substance P at a very high dosage released LH and FSH in vitro[1].

[In Vivo]

[Tyr8]-Substance P shows the activity in contraction of the isolated guinea pig ileum and decrease in systemic blood pressure of dogs[1].

[References]

[1]. Fisher, et al. Hypothalamic hormones. 71. Synthesis and some biological activities of the tyrosine-8 analog of substance P. Journal of Medicinal Chemistry.Volume: 19. Issue: 2. Pages: 325-8. Journal; Article. 1976.

Chemical & Physical Properties

[ Molecular Formula ]:
C63H98N18O14S

[ Molecular Weight ]:
1363.63000

[ Exact Mass ]:
1362.72000

[ PSA ]:
562.16000

[ LogP ]:
3.89970

Related Compounds