trans-Stilbene-d2

Names

[ Name ]:
trans-Stilbene-d2

[Synonym ]:
1-Propene,1,2-dichloro
trans-<1,2-2H2>stilbene
trans-1,3-dichloropropylene
1c,2-dichloro-propene
Propene,1,2-dichloro
trans-1,2-Dichloropropene
1c,2-Dichlor-propen
trans-1,2-dideuteriostilbene

Biological Activity

[Description]:

trans-Stilbene-d2 is the deuterium labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Julia López-Hernández, et al. Trans-Stilbenes in Commercial Grape Juices: Quantification Using HPLC Approaches. Int J Mol Sci. 2016 Oct 24;17(10):1769.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₀D₂

[ Molecular Weight ]:
182.25700

[ Exact Mass ]:
182.10600

[ LogP ]:
3.85700

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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