USP8-IN-2

Names

[ CAS No. ]:
2477651-11-7

[ Name ]:
USP8-IN-2

Biological Activity

[Description]:

USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[Target]

USP8:6.0 μM (IC50)


[References]

[1]. Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H20ClF3N4OS

[ Molecular Weight ]:
444.90

Related Compounds