Metallo-β-lactamase-IN-2

Names

[ Name ]:
Metallo-β-lactamase-IN-2

Biological Activity

[Description]:

Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7), respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 0.1 ± 0.0 μM (VIM-1), 1.3 ± 0.0 μM (NDM-1), 5.0 ± 0.6 μM (IMP-7)[1]

[References]

[1]. Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₉Cl₂NOS

[ Molecular Weight ]:
250.14

Related Compounds

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