SulfaMonoMethoxine-13C6 hydrate

Names

[ CAS No. ]:
1416768-32-5

[ Name ]:
SulfaMonoMethoxine-13C6 hydrate

Biological Activity

[Description]:

Sulfamonomethoxine-13C6 is the 13C6 labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

[2]. Ryuji Ueno. Pharmacokinetics and Bioavailability of Sulfamonomethoxine in Cultured Eel. Fish Pathology,33(4),297-301,1998.10.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Safety Information

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
22-36/37/38-52/53

[ Safety Phrases ]:
26-61

Related Compounds