CRTh2 antagonist 1

Names

[ CAS No. ]:
1379445-54-1

[ Name ]:
CRTh2 antagonist 1

Biological Activity

[Description]:

CRTh2 antagonist 1 is a CRTh2 antagonist with an IC50 of 89 nM。

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Research Areas >> Inflammation/Immunology

[Target]

IC50: 89 nM (CRTh2)[1]


[In Vitro]

CRTh2 antagonist 1 is compound 32[1].

[References]

[1]. Andrés M, et al. 2-(1H-Pyrazol-4-yl)acetic acids as CRTh2 antagonists. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3349-53.


[Related Small Molecules]

Dinoprostone | Prostaglandin E1 | E7046 | ONO-AE3-208 | PF 04418948 | Fevipiprant | grapiprant | TG6-10-1 | Taprenepag | GW 627368 | MRE-269 | Ramatroban | AH 6809 | Laropiprant | AZD1981

Chemical & Physical Properties

[ Molecular Formula ]:
C23H25N3O5S

[ Molecular Weight ]:
455.53

Related Compounds